| abstract |
The invention discloses a conductive hydrogel scaffold material for treating and promoting bone regeneration in cooperation with osteosarcoma, a preparation method and application thereof, wherein the scaffold material comprises the following components in parts by weight: GelMA/oxide hydrogel, PVP-PPy conductive polymer, mechanical property enhancing particles and bone growth promoting elements; wherein, according to the mass ratio GelMA/oxide hydrogel: PVP-PPy conductive polymer: mechanical property-enhancing particles: bone growth promoting elements (11-40): (0.01-1): (0.5-2): (0.5 to 3). The GelMA/oxide hydrogel, the MMT-Sr particles and the PVP-PPy conducting polymer are polymerized, the GelMA/oxide hydrogel can load drugs, the PVP-PPy conducting polymer has excellent photo-thermal conversion performance, and the material can be used as a preparation material for a scaffold for promoting bone tissue regeneration. |