http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113499311-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045 |
| filingDate | 2021-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113499311-B |
| titleOfInvention | Vinpocetine nano-emulsion for nose and preparation method and application thereof |
| abstract | The invention relates to a vinpocetine nasal nano-emulsion, a preparation method and application thereof, wherein the vinpocetine nasal nano-emulsion comprises vinpocetine, an oil phase, an emulsifier and an antioxidant, and contains or does not contain borneol and/or a co-emulsifier according to requirements, and the preferred range of the mass percentage of each component is as follows: 0.1-0.7% of vinpocetine, 0-1.4% of borneol, 1-9% of oil phase, 6-24% of emulsifier, 0-18% of co-emulsifier and 0.025-0.2% of antioxidant. The vinpocetine nasal nanoemulsion prepared by the emulsification method has small and uniform particle size and round and neat appearance. The nasal nano-milk can be used for treating Alzheimer's disease, vascular dementia and other senile dementia and can improve and recover memory. The nasal nano-emulsion has the following advantages: the water solubility of the vinpocetine is improved, the bioavailability and the intracerebral distribution amount of the vinpocetine in blood are improved, the concentration of the vinpocetine in a focus position in the brain is increased, and the disease treatment effect and the medication safety are obviously improved. |
| priorityDate | 2021-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.