http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113491685-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-11 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-11 |
| filingDate | 2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113491685-B |
| titleOfInvention | Composition for inhibiting macrophage activation and application thereof in preparation of anti-inflammatory product |
| abstract | The invention belongs to the technical field of anti-inflammatory drugs, and discloses a composition for inhibiting macrophage activation and application thereof in preparation of an anti-inflammatory product, wherein the composition consists of cinnamaldehyde and Drp1 inhibitor. The mol ratio of the cinnamaldehyde to the Drp1 inhibitor is (0.3-2.3): (0.5 to 3.5). The composition has good anti-inflammatory effect, and can reduce the concentration of single drug by utilizing the synergistic effect of cinnamaldehyde and Drp1 inhibitor, thereby reducing the toxic and side effects of the single drug and reducing the harm to human body. The result of the invention shows that cinnamaldehyde can promote mitophagy, but has no inhibition effect on mitochondrion division, and Drp1 inhibitor can inhibit mitochondrion fission. Therefore, the combination of cinnamaldehyde and Drp1 inhibitor can inhibit inflammatory reaction by acting on different targets, and is expected to be a potential therapy for treating inflammation-related diseases. |
| priorityDate | 2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 178.