http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113481165-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 |
| filingDate | 2021-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113481165-B |
| titleOfInvention | CAR-T secreting bispecific T cell adaptor and its application in the treatment of solid tumors |
| abstract | The present invention relates to a CAR-T secreting a bispecific T cell adaptor and its application in the treatment of solid tumors. The CAR-T secreting a bispecific T cell adaptor, which targets a first antigen, simultaneously expresses and secretes a bispecific T cell adaptor molecule targeting a second antigen, the CAR-T is shown to be responsive to the expressed antigen The lethality of tumor cells, and the overall lethality of tumor cells (including tumor cells that express the second antigen but not the first antigen) are enhanced. The present invention further relates to methods of producing said CAR-T secreting bispecific T cell adaptors. |
| priorityDate | 2020-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 596.