http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113480646-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2021-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113480646-B |
titleOfInvention | Preparation and application of monoclonal antibody specifically binding H1.4 frameshift mutant protein |
abstract | The invention discloses preparation and application of a monoclonal antibody specifically bound with H1.4 frameshift mutant protein. Specifically disclosed is a detection antibody or antigen-binding portion thereof that specifically binds to a H1.4 frameshift mutein, comprising a heavy chain having the amino acid sequence SEQ ID No.1 and a light chain having the amino acid sequence SEQ ID No. 2. The invention prepares the mouse monoclonal antibody aiming at the H1.4 frameshift mutant protein by utilizing the H1.4 frameshift mutant polypeptide hapten for the first time, and the prepared antibody can be specifically combined with the H1.4 frameshift mutant protein, can quickly, sensitively and accurately detect the H1.4 frameshift mutation, provides an essential experimental material for the research of the generation of an autism mechanism caused by the H1.4 frameshift mutation, provides a detection basis for the diagnosis of an autism patient, and has wide application prospect and important significance in the field of the diagnosis or auxiliary diagnosis of autism and the development of targeted drugs of related diseases. |
priorityDate | 2021-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 502.