| abstract |
The invention discloses a hydroxyapatite bone-like material and a preparation method thereof. The bone imitation material of the present invention includes hydroxyapatite ceramic particles, a solvent and a dispersant; the particle size of the hydroxyapatite particles ranges from 0.1 to 10 µm, and the solid phase content ranges from 30 to 66 vol%; the The dispersant is citrate, polyacrylic acid, ammonium polyacrylate or polyacetimide; the content of the dispersant is 0.1-3% of the mass of the hydroxyapatite particle dry powder, and also includes the addition of trace element substances or pharmaceutical raw materials . The present invention can prepare complex and fine micro-scale three-dimensional structures without collapse or fracture during the molding process, and the obtained materials can be used to prepare various ceramic special-shaped parts and structural parts and customized products, including medical implants and tissue engineering scaffolds , the obtained drug-loaded bone-like material can play the dual role of repairing bone defect and drug carrier. |