http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113461716-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-06 |
| filingDate | 2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113461716-B |
| titleOfInvention | A kind of purification method of cefazolam hydrochloride |
| abstract | The invention discloses a method for purifying cefazolam hydrochloride. The cefazolam salt solution is filtered to remove solid impurities, and after adding hydrochloric acid to adjust the pH to neutrality, adding water to separate out the cefazolam solid; (3) reacting the precipitated cefazolam solid with hydrochloric acid to make the primary cefazolam hydrochloride (4) The primary fine cefazolam hydrochloride is vacuum-dried to obtain the fine cefazolam hydrochloride. The invention utilizes the principle of poor water solubility of cefazolam, alkalizes the crude cefazolam hydrochloride and re-precipitates it, reduces the residual amount of dissolved organic matter, and removes excess water through vacuum drying, so as to obtain a purer cefazolam hydrochloride fine product. |
| priorityDate | 2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.