http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113461587-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate | 2020-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113461587-B |
| titleOfInvention | Small molecule inhibitor YAP1-Y7 aiming at YAP1 and application thereof |
| abstract | The invention belongs to the field of molecular targeted therapy, and particularly relates to a small molecular inhibitor YAP1-Y7 of Yes-associated protein 1 (YAP 1) and application thereof in tumor treatment. A small molecule inhibitor YAP1-Y7 aiming at YAP1, wherein the chemical structural formula of the small molecule inhibitor YAP1-Y7 is as follows: . The small molecule inhibitor can inhibit YAP1, and inhibit YAP1 to reduce YAP1-TEAD compound, thereby inhibiting tumor cell proliferation. The small molecule inhibitor is applied to the preparation of the medicine for treating gastric cancer. Compared with the known inhibitor, the small-molecule inhibitor aiming at YAP1 provided by the invention has strong affinity. Can be used as a new anti-tumor drug to completely eliminate tumors and stem cells, and has wide application prospect. |
| priorityDate | 2020-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 161.