http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113453707-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ae7bc470b590116f17769a5b53f38cc |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-015 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 |
filingDate | 2019-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ead769d4096980985502a5b1672130d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3510e0220c3059f6a859ab6a064ecb2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7398d23a348e3b429a02eea300f6f736 |
publicationDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113453707-A |
titleOfInvention | RNA for malaria vaccine |
abstract | The present invention relates to coding RNAs for malaria vaccines. The coding RNA comprises at least one heterologous untranslated region (UTR), preferably 3'-UTR and/or 5'-UTR, and a coding region encoding at least one antigenic peptide or protein derived from Plasmodium, In particular, at least one antigenic protein derived from the circumsporozoite protein (CSP) of Plasmodium parasites, such as Plasmodium falciparum. The present invention also relates to compositions and vaccines comprising said encoding RNA in combination with polymeric carriers, polycationic proteins or peptides, or lipid nanoparticles (LNPs). Furthermore, the present invention relates to kits, in particular kits comprising encoding RNA or compositions or vaccines. The present invention also relates to methods of treating or preventing malaria, as well as first and second medical uses of the encoding RNAs, compositions, vaccines and kits. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115429741-A |
priorityDate | 2018-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1119.