| abstract |
Liquid, gel, and semi-solid compositions are provided that contain a naloxone base, or an isomer or derivative thereof, and one or more non-aqueous solvents, and optionally a viscosity modifier. Also provided is a method of treating an individual exhibiting symptoms of respiratory depression associated with known or suspected opioid overdose, the method comprising administering a naloxone base, or an isomer or derivative thereof, in one or more Liquid, gel or semi-solid formulations of solutions in a non-aqueous solvent. |