http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113444107-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113444107-B |
| titleOfInvention | Synthetic method and anticancer activity of succinimide spiro-fused sultams compound |
| abstract | The invention discloses a synthetic method and anticancer activity of succinimide spiro-fused sultams, belonging to the technical field of organic synthesis and drug discovery. The succinimide spiro-fused sultam compounds 3 are efficiently synthesized by the series reaction between the arylsulfonamide 1 and the N-substituted maleimide 2 in the presence of a rhodium catalyst and an additive. The synthetic method has the advantages of simple and easily obtained raw materials, simple and convenient operation, wide substrate application range, high atom economy, sustainability and the like. Meanwhile, the compounds have obvious activity of resisting cancer cells such as REC-1, Ramos and the like, so the compounds have potential medicinal value. |
| priorityDate | 2021-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.