http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113413462-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6949 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21079 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
| filingDate | 2021-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113413462-B |
| titleOfInvention | Nanomaterials for high-efficiency treatment of intracellular bacteria by simulating natural killer cells and their preparation methods and applications |
| abstract | The invention discloses a nanomaterial for simulating natural killer cells to efficiently treat intracellular bacteria and a preparation method and application thereof. The nanomaterials for the efficient treatment of intracellular bacteria by simulating natural killer cells include disulfide bond-doped dendritic mesoporous silica as a carrier and a protease loaded in the pores of the carrier; the protease is preferably a pore and/or granzymes. The nanomaterial for simulating natural killer cells to efficiently treat intracellular bacteria uses disulfide bond-doped dendritic mesoporous silica as a carrier, and responsively degrades and releases protease under the specific redox potential possessed by the intracellular bacteria model. Not only can it circumvent the killing of normal cells because it is hardly degraded in normal cells, but also can effectively treat intracellular bacteria by mimicking natural killer cells through specific response release to achieve bactericidal treatment of infected cells and further cause organisms. Spontaneous immunomodulatory mechanisms to promote efficient antibacterial and anti-infective applications. |
| priorityDate | 2021-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.