http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113413398-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d94573ab2c57e8b193f3a22accddf9fe |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-60 |
filingDate | 2021-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a78ac4c3e077525201a4d072822a018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38141813fba0350644fee2fa7bdd589b |
publicationDate | 2021-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113413398-A |
titleOfInvention | Fish egg extract and its application |
abstract | The present invention relates to the field of polypeptides, in particular to fish egg extracts and applications thereof. The freshwater fish roe extract and seawater fish roe extract provided by the present invention and their different components (5-10kDa, <5kDa) all have DPPH free radical scavenging activity, indicating that the fish roe extract has a certain degree of in vitro antioxidant effect . Fish egg extract can inhibit the proliferation of breast cancer cells MCF-7 and induce MCF-7 cell apoptosis, such as apoptosis morphological changes, Annexin V/PI positive expression, etc.; MCF-7 can be seen 24h after fish egg extract treatment of cells Intracellular reactive oxygen species and superoxide production and mitochondrial depolarization. The results suggest that fish egg extract may have anti-breast cancer therapeutic potential based on apoptosis. |
priorityDate | 2021-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.