| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70596 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate |
2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113412818-B |
| titleOfInvention |
Non-human animals with humanized cluster of differentiation 274 genes |
| abstract |
The present invention provides non-human animals, methods and compositions for making and using the non-human animals, wherein the non-human animals comprise humanization of the cluster of differentiation 274 (CD274) gene. Such non-human animals can be described in some embodiments as having genetic modifications to the endogenous CD274 gene such that the non-human animals express programmed cell death ligand 1 (PD-L1) polypeptides comprising Human parts and endogenous parts (eg, non-human parts). |
| priorityDate |
2014-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |