http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113412817-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate | 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113412817-B |
titleOfInvention | IBS-D Experimental Animal Model Method for Improving Molding Rate and Decreasing Mortality |
abstract | The invention provides an IBS-D experimental animal model method for improving the molding rate and reducing the mortality rate, which selects adult mice as the modeling experiment object, and includes the following steps: Step 1, colorectal dilation: first, lightly touch the anus of the mouse , make the mouse defecate; then use a tracheal cannula with a balloon to insert it into the mouse anus, wherein the balloon end of the tracheal cannula is located in the mouse anus, and the outer end of the tracheal cannula is fixed at the root of the mouse tail; then the mouse is placed in a transparent observation Indoors, the transparent observation room can limit the left and right movement of the mouse; after the mouse is calm, inject gas into the balloon of the tracheal intubation, so that the balloon has a certain expansion pressure, and stimulate the colorectum of the mouse; Step 2, chronic restraint stress: the mouse The transparent observation room was taken out, and the abdomen and limbs of the mice were immobilized in a supine position. The invention can better completely replicate the disease characteristics, at the same time, it can reduce the mortality rate and improve the molding rate; meanwhile, it can make the modeling effect more durable and stable. |
priorityDate | 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.