http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113406230-A

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filingDate 2021-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0988a733a83ee1befe7b3013613f9366
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publicationDate 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113406230-A
titleOfInvention A kind of determination method of dissolution curve of ulipristal acetate solid preparation
abstract The invention relates to the technical field of drug quality control, in particular to a method for determining the dissolution curve of a solid preparation of ulipristal acetate. In this method, a solvent containing Tween 80 is used as the dissolution medium, and under stirring, the paddle method is used to detect the cumulative dissolution rate of ulipristal acetate solid preparation in the dissolution medium at different dissolution time points, and then the dissolution curve is drawn; Tween 80 The volume percent concentration in the dissolution medium is 0.1% to 2%. The method of the invention adds the surfactant Tween 80 to the dissolution medium for the evaluation of the dissolution curve of the ulipristal acetate tablet, scientifically and objectively evaluates the quality of the ulipristal acetate tablet, and can be used for the quality of the generic drug and the original research drug. Consistency (similarity) evaluation work can also provide assurance for the consistency of drug batch quality.
priorityDate 2021-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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