http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113403366-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9121 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
| filingDate | 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a616f0763ff34c4808bd0cffcce02a42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13d62270e230414c9d38be91a4fba04c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab4bca6ae5a6e320b086c5e4b0a66ddd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7f9687677a4b2df628c9e631dd93ecd |
| publicationDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113403366-A |
| titleOfInvention | A kind of zirconium ion mediated nano sensor and preparation method and application |
| abstract | The present disclosure relates to the technical field of kinase activity detection, in particular to a zirconium ion-mediated nanosensor, a preparation method and application thereof. The nanostructure includes a single quantum dot QD and a capture probe, and streptavidin is modified on the single quantum dot On the surface of the QD, a phosphate group and biotin are each modified at both ends of the capture probe; the capture probe is self-assembled onto the surface of the single quantum dot QD using biotin-streptavidin. In the presence of PKA/PNK, they catalyze the phosphorylation of Cy5-modified peptide/DNA and assemble to the surface of individual QDs through the coordination of Zr 4+ with phosphate groups, forming QD‑Zr 4+ ‑Cy5 nanostructures and leading to QDs Fluorescence resonance energy transfer (FRET) occurs with Cy5. With single-molecule detection, the FRET signal can be easily measured. |
| priorityDate | 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.