http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113403237-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-31 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-48 |
| filingDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113403237-B |
| titleOfInvention | Gentamicin sulfate prepared by enhanced microbial fermentation and application method thereof |
| abstract | The invention claims an enhanced microbial fermentation preparation gentamicin sulfate and an application method thereof, wherein the enhanced microbial engineering bacteria are a Micromonospora purpurea (Micromonospora purpurea) C21591 strain. The engineering bacteria of the oriented high-yield gentamicin C2 obtained by screening can be used for oriented high-yield gentamicin C2, the component ratio of gentamicin C2 is improved to more than 85% of the existing component ratio from about 15%, the maximum fermentation titer of the optimized formula is 1184U/mL, and the titer is improved by 42% compared with that of the original formula. Compared with the original strain, the yield of the gentamicin C2 is improved by 3 times, and other isomerous isomers or impurities are basically not contained, so that a large amount of cost is saved, and the industrialization requirement is met. |
| priorityDate | 2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.