http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113402516-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 2021-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113402516-B |
titleOfInvention | A method for the synthesis of isoquinolinone derivatives by the room temperature C-H activation/cyclization cascade reaction of N-chloroamides |
abstract | The present invention provides a method for synthesizing isoquinolinone derivatives by a room temperature C-H activation/cyclization cascade reaction of N -chloroamides. Taking N -chloroamide as the guiding group and alkynedione as the coupling reagent, the C-H activation/cyclization cascade reaction at room temperature is realized under transition metal catalysis to synthesize isoquinolinone derivatives. Compared with other methods, the present invention has the following significant advantages: the C-H activation/cyclization cascade reaction at room temperature is mild, green and safe; the substrate is suitable for a wide range, and the terminal alkyne is tolerant. |
priorityDate | 2021-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.