| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3612
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3604
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y70-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B33Y70-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 |
| filingDate |
2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113398332-B |
| titleOfInvention |
3D bionic bioscaffold containing stem cell exosomes and application |
| abstract |
The invention provides a 3D bionic scaffold containing stem cell exosomes and application thereof, the bionic scaffold utilizes methacrylic anhydride gelatin, oxidized hyaluronic acid and dopamine modified hyaluronic acid as main materials, cartilage acellular matrix (DCM) or bone acellular matrix (DBM) is added to simulate a cartilage or subchondral bone microenvironment and mesenchymal stem cell exosomes (Exos) are added to be mixed to serve as bio-ink, and 3D printing bio-ink is used for constructing a composite scaffold containing Hydrogel-DCM-Exos and Hydrogel-DBM-Exos, the composite scaffold simulates the biological activity of cartilage and subchondral bone, and the healing of articular cartilage and subchondral bone is promoted at the same time. |
| priorityDate |
2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |