| abstract |
The present invention relates to an aromatic heterocyclic derivative regulator, its preparation method and application. In particular, the present invention relates to the compound represented by the general formula (I), its preparation method and the pharmaceutical composition containing the compound, and as a KRAS G12C mutation inhibitor, in the treatment of leukemia, neuroblastoma, melanoma, breast cancer The use of diseases or conditions such as cancer, lung cancer and colon cancer, wherein each substituent in the general formula (I) is as defined in the specification. |