| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afa9cd0479ca565bc3cefcaab4bb0d8a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0325
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7158 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate |
2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a9b4ca72cf5d2ea719004a0ef860d2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b776bd5704620b0d0eddc387d529783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d409f66112f7b650abe2aca41ca96b34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39b810f33073421c6191b62f33f63eb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a6b7d91f1f00b7090fc9711e804e24d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b286da6736c8972e2b16037b013441da |
| publicationDate |
2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113388640-A |
| titleOfInvention |
Humanized non-human animal of CCR4 gene and its construction method and application |
| abstract |
The invention provides a construction method of a CCR4 gene humanized non-human animal and its application in the field of biomedicine. The nucleotide sequence encoding the human CCR4 protein is introduced into the non-human animal genome by means of homologous recombination. Animals can normally express human or humanized CCR4 protein, which can be used as an animal model for the study of human CCR4 signaling mechanism and drug screening for tumors and immune diseases. It has important application value for the development of new drugs for immune targets. The present invention also provides a humanized CCR4 gene, a humanized CCR4 protein, and a targeting vector. |
| priorityDate |
2020-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |