| abstract |
The invention relates to an estrogen-progestin mixed gel preparation and a preparation method. The adopted technical scheme is: including the following components by weight percentage: including progesterone 0.1%-8%, estradiol 0.1%-3%, azone 1%-3%, plant dermal agent L40 or S60.1% ‑4%, ethanol 10%‑30%, propylene glycol 3%‑15%, carbomer 0.5%‑1%, triethanolamine 0.03%‑0.05%, in a stainless steel container, add ethanol, progesterone, and estradiol in sequence , propylene glycol, azone, carbomer, plant transdermal agent L40 or S6, then add triethanolamine after heating and stirring, after mixing and stirring, adjust the pH value to the range of 6-7, and stir to obtain gel, Can be prepared. The beneficial effects of the present invention are: assisting reproduction, regulating menstrual disorders, artificial menstruation, protecting breast and uterus, preventing cancer, breast enhancement, postpartum maintenance, improving sexual life quality, beauty and anti-aging, preventing climacteric syndrome and regulating climacteric symptoms, improving metabolism , Reduce abdominal fat accumulation, good transdermal effect. |