abstract |
Disulfide compounds of formula (I), wherein Y is a sulfonyl or sulfinyl group, Z is a phenyl or substituted phenyl group, and other variables are as defined in the claims; pharmaceutical compositions comprising these compounds and for the preparation of these compound method. These compounds are useful in therapeutic methods to treat microbial infections, inflammation, and to reduce the formation of blood clots, and have non-therapeutic uses as antimicrobial, anti-inflammatory, and antithrombotic agents. |