http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113373103-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-38 |
| filingDate | 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113373103-B |
| titleOfInvention | A kind of method for improving 5-hydroxytryptophan production |
| abstract | The invention provides a method for increasing the yield of 5-hydroxytryptophan. In the acid-producing stage in the middle stage of fermentation, the ventilation volume is reduced, the dissolved oxygen is reduced, and citric acid is added in flow to ensure sufficient reducing power in the synthesis process of BH4. Reduce the rate of sugar supplementation and reduce the accumulation of tryptophan; this method increases the production of 5-HTP by controlling the dissolved oxygen to a sub-appropriate amount of cells, adding citric acid to inhibit the EMP pathway, enhancing the HMP pathway, and reducing the acceleration rate of glucose flow in the fermentation process, reducing intermediate The product tryptophan solves the problems that tetrahydropterin is oxidatively consumed in the biological fermentation process, the reducing power of the synthesis process is insufficient, and the excessive accumulation of tryptophan affects the production of 5-HTP. |
| priorityDate | 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.