http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113372344-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d22d287b9da0b1ae75c4aa229b3fd793 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b69481e1491aba750e8c0420dff7260 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b18e26aa8b4f7fe5dca25789fc9c3f45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18c5e4ac1df8edf41406e30fa6897926 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0069467b86490e741962a52b7dcf0ce2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c27d621f93250540a9be301f1e899c5f |
| publicationDate | 2021-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113372344-A |
| titleOfInvention | A kind of synthetic method of chloro six-membered nitrogen-containing heterocyclic imidazole compounds |
| abstract | The invention discloses a method for synthesizing a chloro six-membered nitrogen-containing heterocyclic imidazole compound, and specifically discloses the reaction of compound I with phosphorus oxychloride and an organic base in the presence or absence of a solvent to obtain the compound shown in formula II. The compound shown; wherein, X is N or C(R 3 ); Y is N or C(R 2 ); Z is N or C(R 1 ); R 1 , R 2 and R 3 are independently hydrogen, halogen or C 1 -C 6 alkyl. The synthesis method of the invention is easy to operate, completes the ring closure and chlorination steps in one pot, the used reagents are less polluted, traditional reagents such as chloroacetaldehyde or sulfuric acid are eliminated, and the product yield and purity are obviously improved. |
| priorityDate | 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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