http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113372223-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84620139f03243333ece9d744568374d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 |
| filingDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87f9161bc2a5350cf5998273ba00ab52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_272c7ed757fd0d29e088beb31c98c620 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c548ea4c1b25408eefda1a25ca31f96e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be98c46bd208ca99d72ce97a85835359 |
| publicationDate | 2021-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113372223-A |
| titleOfInvention | A kind of preparation method of 2-fluoro-3-bromo-benzylamine |
| abstract | The invention provides a method for synthesizing 2-fluoro-3-bromo-benzylamine, comprising the following steps: dissolving 2-fluoro-3-bromoxynil in an organic solvent to form a 2-fluoro-3-bromoxynil solution , add dropwise BH 3 .Me 2 S (borane dimethyl sulfide) solution to the 2-fluoro-3-bromoxynil solution to react, then dropwise add methanol to quench the reaction until no hydrogen is released; after the reactant is concentrated, add Dissolved in methanol, refluxed and stirred for 2-5 h, after removing the solvent, the concentrate was passed through a chromatographic column and eluted to obtain 2-fluoro-3-bromo-benzylamine. The synthesis method has low production cost, high product yield and purity, simple operation, and is suitable for industrial mass production. |
| priorityDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.