http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113368045-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
filingDate | 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2023-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113368045-B |
titleOfInvention | A drug-loaded nanomicelle responsive to magnetic oxidation and its preparation method and application |
abstract | The invention relates to the field of nanomedicine, in particular to a magnetic oxidation-responsive drug-loaded nano-micelle and a preparation method and application thereof. The magnetic oxidation-responsive drug-loaded nanomicelle provided by the present invention loads oil-soluble Fe 3 O 4 nanoparticles in a micelle system, which can be wrapped in the hydrophobic core of the oxidation-sensitive micelle. In an oxidizing environment, the micelles are oxidized to disassemble and release Fe3O4 nanoparticles to achieve nanoscale conversion. The loaded drug is released quickly after reaching the target site, shortening the residence time in the body. The application of it in the transport carrier of anti-tumor drugs can realize the effective transportation of nano drug particles in the process of blood circulation and the accumulation inside the tumor, and enhance the penetration of anti-tumor drugs to tumors. |
priorityDate | 2021-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.