http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113350525-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 |
| filingDate | 2021-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113350525-B |
| titleOfInvention | A kind of porous starch-loaded artemisinin hydroxypropyl-β-cyclodextrin inclusion compound and its preparation method and application |
| abstract | The invention provides a porous starch-loaded artemisinin hydroxypropyl-β-cyclodextrin inclusion compound and a preparation method and application thereof, belonging to the technical field of medicine. The artemisinin hydroxypropyl-β-cyclodextrin inclusion complex supported on porous starch provided by the present invention includes porous starch and artemisinin hydroxypropyl-β-cyclodextrin inclusions loaded in the pores of the porous starch The artemisinin hydroxypropyl-β-cyclodextrin inclusion compound includes artemisinin and hydroxypropyl-β-cyclodextrin coated on the surface of the artemisinin. The invention uses fat-soluble artemisinin as an active ingredient, uses hydroxypropyl-β-cyclodextrin as an inclusion material, and uses porous starch as a carrier, which can significantly improve the water solubility of artemisinin, thereby improving its bioavailability and antimalarial activity; and the porous starch-loaded artemisinin hydroxypropyl-β-cyclodextrin inclusion complex provided by the invention has good biological safety, and can avoid possible hidden dangers and toxic and side effects of existing artemisinin derivatives. |
| priorityDate | 2021-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.