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filingDate 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113341044-A
titleOfInvention A method for identifying drowning based on metabolomic markers and its application
abstract The invention belongs to the technical field of forensic medicine and biomedicine, and particularly relates to the application of metabolites screened based on metabolomics in judging whether an early water corpse is drowning. The marker for judging whether the corpse in the water is drowning in the early stage is characterized in that the marker includes any one or a combination of the following 14 small molecule metabolites: lactic acid, mevalonic acid, Phenylacetylglycine, tetradecanedioic acid, inosine, malic acid, beta hydroxybutyrate, undecanoic acid, glycylleucine, corticosterone, thiamine, acetylcarnitine, alanylleucine acid and kynurenine. The method for identifying drowning based on metabolomics markers provided by the present invention has higher predictive ability based on the comprehensive analysis of a large number of biomarkers than the method using one or several biomarkers. The content of endogenous target biomarkers, combined with machine learning algorithms, can easily and accurately identify fresh drowned corpses, which is expected to provide more favorable help for case detection in forensic practice.
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