http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113336726-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-33 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-33 |
| filingDate | 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113336726-B |
| titleOfInvention | A kind of preparation method of Bu Waracetam intermediate |
| abstract | The invention provides a kind of preparation method of buvaracetam intermediate (R)-3-propyl-γ-butyrolactone, the method is starting raw material with 4-chloro-4-oxobutyric acid methyl ester, By connecting the chiral auxiliary group, introducing the R-configuration propyl group, removing the ligand, reducing the carboxyl group, and finally esterifying into a ring to obtain (R)-3-propyl-γ-butyrolactone; the synthetic route of the present invention cleverly utilizes the chiral Sexual auxiliary agent (R)-4-benzyl-2-oxazolidinone optimizes the reaction conditions, has the advantages of few reaction steps, high yield, good reaction stereoselectivity, etc., while raw materials are cheap and easy to obtain, easy to operate, It is safe and has good industrial application prospects; |
| priorityDate | 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.