http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113332951-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2509-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-3234 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-28 |
filingDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113332951-B |
titleOfInvention | A magnetic nanomaterial for efficiently enriching circulating tumor cells and its preparation method |
abstract | The invention discloses a magnetic nano-material for efficiently enriching circulating tumor cells and a preparation method thereof, which belongs to the technical field of cancer diagnosis materials and solves the problems of high price, easy inactivation, and destruction of cell activity in traditional technologies, and comprises the following steps : Step A: Vigorously stir anhydrous ferric chloride, trisodium citrate, and ethylene glycol for 15 minutes; Step B: Take 1.2 g of sodium acetate and add it to the mixture in Step A, heat and stir for 30 minutes until completely dissolved; Step C: Put the mixture in step B in a polytetrafluoroethylene-lined autoclave, slowly heat up to 200°C, and keep the reaction for 10 hours; Step D: Take out the yellow supernatant and the lower black product of the mixture in step C, and repeat Washing to obtain Fe 3 O 4 nanoparticle solution; step E: Add CuCl 2 and TA dropwise to the Fe 3 O 4 nanoparticle solution obtained in step D to obtain magnetic nanoparticle Fe 3 O 4 @TA/Cu II , which realizes the Efficient isolation and non-destructive release of tumor cells. |
priorityDate | 2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.