| abstract |
The invention discloses a traditional Chinese medicine composition with the effect of delaying the aging of myocardial cells, a preparation method and application thereof. The traditional Chinese medicine composition of the invention is composed of active ingredients and medicinal excipients, wherein the active ingredients include: ginseng, Panax notoginseng, Chuanxiong and Dendrobium. The composition of the present invention can regulate telomeres and telomerase to interfere with D-galactose-induced cardiomyocyte senescence, especially involving regulating the expression of AGEs and/or p53 markers. In addition, the composition of the present invention is based on the scientific compatibility of the effective components of traditional Chinese medicine, and the components have a synergistic effect, thereby effectively delaying the aging of cardiomyocytes. |