http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113310589-A

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filingDate 2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af9412f507f70c134738a870c9303654
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publicationDate 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113310589-A
titleOfInvention Ratio type surface enhanced Raman spectrum nano thermometer, preparation method and application thereof
abstract The invention discloses a ratio type surface enhanced Raman spectroscopy nano thermometer, a preparation method and application thereof. The thermometer is of a multilayer nano structure, gold shell nanoparticles are used as a substrate material, a polymer p (NIPAm-co-AAm) wrapping layer is used as a temperature-sensitive response material, gold ball adsorbing nanoparticles are used as an SERS probe layer, and 4-ATP and DTNB are used as Raman signal molecules. The volume change of the temperature-sensitive polymer is triggered by the change of the temperature, so that the distance between the gold sphere nanoparticles and the gold shell nanoparticles is changed, and further the SERS signal of the 4-ATP modified on the surfaces of the gold sphere nanoparticles is changed. Ratiometric signal of SERS signal of DTNB surface-modified with gold-shell nanoparticle surface and SERS signal of 4-ATP I R (I R = I 1074 / I 1327 ) The temperature sensing is realized, the detection result is reliable, and the detection sensitivity is high.
priorityDate 2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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