| abstract |
The present invention addresses the problem of providing a novel 3-azabicyclo [3.1.0]]A crystal of a salt of a hexane derivative, which is a high-purity crystal having good physical properties (stability, solubility, etc.) among compounds having a mu opioid receptor antagonistic action with little side effect and high safety, and a pharmaceutical use thereof. The crystal is a compound represented by the formula (I) and is formed from hydrochloric acid, hydrobromic acid and oxalic acidCrystals of a salt or a hydrate of the salt of the acid selected from the group (in the formula (I), R 2 Represents a hydrogen atom or a halogen atom, R 1 Represents a group selected from the group formed by formulae (AA, BB, CC, DD). |