http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113307759-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 |
| filingDate | 2021-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113307759-B |
| titleOfInvention | Cyanine near-infrared fluorescent probe and preparation method and application thereof |
| abstract | The invention discloses a cyanine near-infrared fluorescent probe and a preparation method and application thereof, wherein the cyanine near-infrared fluorescent probe disclosed by the invention takes hydrolysis of esterase to an ester bond bonded in cyanine dye as a basic action mechanism, and takes H-type aggregate luminescence of cyanine-amino alcohol as a fluorescent signal reporting group. When esterase is added to the system, ester bonds in the Cy-NE structure are cut by the esterase, and Smiles rearrangement reaction is caused by O-ions, thereby causing the color and fluorescence of the solution to change. The invention researches the recognition effect of the cyanine near-infrared fluorescent probe on esterase by a colorimetric method, an ultraviolet-visible absorption spectrum method and a fluorescence spectrum method, and the result shows that the near-infrared fluorescent probe can efficiently and selectively recognize the esterase in a PBS (phosphate buffer solution) system and has high response sensitivity on the esterase. |
| priorityDate | 2021-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.