| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-65 |
| filingDate |
2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e98e3dec9b36641c56311f1e5df8e338
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac7df3c0322bd25c8b94d2949a102f32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ae3cbf8a060bc476ec48844af99a410
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4bf01665947dc3415bdb1069055259b |
| publicationDate |
2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113293139-A |
| titleOfInvention |
Efficient selectivity for recombinant proteins |
| abstract |
The present invention provides a novel expression system comprising mammalian selectable markers that facilitate desired post-translational modifications of glycoproteins. Specifically, the present invention includes methods and compositions for achieving optimal recombinant protein expression in mammalian cells by employing a selectable marker system based on the GPT gene of mammalian origin. The present invention includes methods for promoting selectivity of recombinant proteins and increasing expressed copies and protein yields in mammalian cells, and methods using the GPT expression system. |
| priorityDate |
2014-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |