http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113292615-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 |
| filingDate | 2020-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113292615-B |
| titleOfInvention | A kind of serotype VIII group B streptococcus oligosaccharide fragment and its preparation method and application |
| abstract | The present invention relates to a serotype VIII group B streptococcus oligosaccharide fragment and its preparation method and application. The oligosaccharide fragments prepared by the invention are repeating fragments of different reducing ends of serotype VIII group B Streptococcus, and are prepared by using various protected monosaccharide modules as raw materials, and sequentially performing glycosidation reactions through convergent glycosylation assembly. , wherein the C-1 position of the pyranosyl group of each reducing end of the oligosaccharide fragment is modified by an aminoalkane chain, which can be conjugated with a protein to prepare an oligosaccharide-protein conjugate, and then conduct related immunological studies. The preparation method of the invention has the advantages of reasonable design, strong operability, simple separation, high product yield and good purity. It is of great significance to develop the corresponding serotype VIII group B Streptococcus saccharide vaccine by synthesizing polysaccharide repeats with different reducing ends for immunological research. |
| priorityDate | 2020-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 95.