http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113292586-B

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filingDate 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113292586-B
titleOfInvention Hybrid material and application thereof in lipoic acid single-molecule quantitative detection
abstract The invention discloses a hybrid material and application thereof in lipoic acid single-molecule quantitative detection, wherein the hybrid material is prepared by carrying out esterification reaction on diimine and oil-soluble carbon quantum dots with carboxyl groups on the surface according to the molar ratio of 1: 1; the diimine has the structure shown as follows: the organic components in the hybrid material fluorescent probe enhance the absorption of the excitation light energy, and transfer the absorbed energy to the carbon quantum dots to enhance the luminous intensity of the carbon quantum dots. The lipoic acid is added into the hybrid material, the disulfide bond and the carboxyl of the lipoic acid can form hydrogen bonds with the hybrid material, the binding force between the hybrid material and lipoic acid molecules is enhanced, the quantitative detection of the lipoic acid is realized, and the lipoic acid has higher sensitivity compared with a high performance liquid chromatography.
priorityDate 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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