http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113281389-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fb38ebd40c70e97cc5f1519c6699162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3271 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327 |
| filingDate | 2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28a673991c31c8c49f4b2a5dfbe848da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc25420b4a3261e8baefe44a6611e9c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4317b9f698ba64dc5ce41811aef60d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fba381661ec840eefa32e5ae07a0a93e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a8a968a3fe6bc812f55ef815af2cc27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7998830f89c6573aafac0702aa5f63ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee379d7801fa670beb6f3c186b5e435e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e398c387db2a55741fb33a08e023def7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bfa2ea20fdf15e3a3da93c8980c1b09 |
| publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113281389-A |
| titleOfInvention | Preparation method of electrochemical immunosensor based on 2,4, 6-triaminopyrimidine regulation and control graphite-like-phase carbon nitride |
| abstract | The invention relates to a preparation method of an electrochemical immunosensor based on 2,4, 6-triaminopyrimidine-regulated graphite-like-phase carbon nitride. According to the invention, in a manner of constructing the sandwich type electrochemical sensor, the graphite-like carbon nitride regulated and controlled by 2,4, 6-triaminopyrimidine is combined with the neuron-specific enolase primary antibody to form a primary antibody marker, and the Fe-ZIF loaded copper sulfide quantum dot composite material is combined with the neuron-specific enolase secondary antibody to form a secondary antibody marker, so that the construction process of the sensor is simplified. Through the copolymerization of the 2,4, 6-triaminopyrimidine and the melamine which is the precursor of the graphite-like carbon nitride, part of nitrogen atoms in a triazine ring structure are accurately replaced by carbon atoms, and the electronic environment of the graphite-like carbon nitride network structure is improved. With 2,4, 6-triaminopyrimidineThe controlled graphite-like carbon nitride is used as a substrate luminescent material, and provides a strong and continuous stable electrochemiluminescence signal required by the sensor. The Fe-ZIF loaded copper sulfide quantum dots are used for marking secondary antibodies of neuron-specific enolase to serve as secondary antibody markers, the sandwich quenching type electrochemical immunosensor is constructed, the ultra-sensitive detection of the neuron-specific enolase is realized, and the detection limit is 21.6 fg mL ‑1 。 |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114609218-A |
| priorityDate | 2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.