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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16
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filingDate 2021-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113278041-B
titleOfInvention Nucleoside phosphate and its synthesis method and application in preparing medicine for anti hepatitis virus
abstract The invention belongs to the technical field of medicinal chemistry, and particularly relates to nucleoside phosphate and a synthesis method thereof, and pharmaceutical application of the nucleoside phosphate in resisting hepatitis viruses. The nucleoside phosphate is 2-sulfo-N-hydroxyl cytosine ribonucleoside phosphate, and the synthetic method has simple steps and high product yield. Experiments prove that the compound 2-sulfo-N-hydroxycytosine ribonucleoside phosphate has good inhibition effect on HBV DNA secreted by HepG2.2.15 cells, has anti-hepatitis virus activity and provides a good choice for treating viral hepatitis.
priorityDate 2021-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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