http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113278026-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2021-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113278026-B |
| titleOfInvention | A kind of siberian compound with antitumor activity and preparation method and application thereof |
| abstract | The invention discloses a siberian compound with antitumor activity, a preparation method and application thereof, and belongs to the field of medicine. In the present invention, the 80% ethanol extract of the dried and ripe fruits of Brachys chinensis is depigmented by a macroporous resin, and then divided into sections by a positive silica gel column, and the ethyl acetate (volume ratio: 85:15, 75:25, 55) : 45, 35:65), dichloromethane-methanol (volume ratio 95:5, 0:100) carried out gradient elution successively; 100%), polyamide column chromatography was eluted with methanol-water (30%), and then separated and purified by gel and high performance liquid phase HPLC; finally, its chemical structure was identified by technologies such as high-resolution mass spectrometry and NMR. The compounds of the present invention can be used for preparing anti-pancreatic cancer drugs or as lead compounds for the development of anti-pancreatic cancer drugs. |
| priorityDate | 2021-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.