http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113274352-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
| filingDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113274352-B |
| titleOfInvention | A kind of nano preparation and its preparation method and application |
| abstract | The invention discloses a nano-formulation, a preparation method and application thereof. The nano-formulation comprises nano-micelles, anti-tumor drugs and immunomodulators encapsulated in the nano-micelles, and the nano-micelles are composed of TfR-T12 -PEG-PLGA and TATH7-PEG-PLGA are self-assembled; the TfR-T12-PEG-PLGA is obtained by condensation reaction between the amino group in the TfR-T12 short peptide and the carboxyl group in the PEG-PLGA; the TATH7-PEG ‑PLGA is obtained by the condensation reaction between the amino group in TATH7 short peptide and the carboxyl group in PEG‑PLGA. As a drug carrier, the nanomicelles can simultaneously deliver antitumor drugs such as paclitaxel and immunomodulators such as migimazole, so that they can smoothly cross the blood-brain barrier, achieve targeted drug delivery, and regulate the immunosuppressive phenomenon in the tumor microenvironment. |
| priorityDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 206.