http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113265456-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-166 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-93 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate | 2021-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-113265456-B |
titleOfInvention | A combination of primers and probes for detecting high-grade cervical lesions and methylation of cervical cancer-related genes |
abstract | The invention discloses a primer and a probe for detecting the degree of methylation of high-grade cervical lesions and cervical cancer-related genes, which are used to detect the methylation of human EPB41L3 gene 425, 427, and 438, and virus HPV16L1 gene 6367, 6389 Site methylation and HPV18L2 gene 4256, 4261, 4265, 4269, 4275 and 4282 site methylation. After a lot of screening and optimization in the present invention, the detection limits of the finally obtained methylation-specific primers and probes for EPB41L3 gene, HPV16L1 gene and HPV18L2 gene are all within 1%. The present invention solves the problem of insufficient correlation between the existing methylation detection results and cervical high-grade lesions and cervical cancer, realizes more accurate and effective technologies for auxiliary diagnosis, shunt management and prognosis judgment of cervical high-grade lesions and cervical cancer, and improves cervical cancer. Efficiency of cancer screening. |
priorityDate | 2021-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 209.