| abstract |
The invention belongs to the field of medicine and provides an imidazo[1,5-a]pyrazine-8-amine compound, a preparation method, a pharmaceutical composition and an application. The imidazo[1,5-a]pyrazine-8-amine compound is a compound having the structure of formula I or a pharmaceutically acceptable salt thereof. The structure of the formula I is: , wherein, R 1 represents a substituted or unsubstituted phenyl or aromatic heterocyclic group. The imidazo[1,5-a]pyrazine-8-amine compound can be used as an effective BTK inhibitor, and has strong inhibitory activity and less side effects. The pharmaceutical composition comprising the imidazo[1,5-a]pyrazine-8-amine compound also has good antitumor pharmacological activity. |