http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113264868-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-004 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-46 |
| filingDate | 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113264868-B |
| titleOfInvention | A kind of improved synthetic method of 1-benzyl-3-piperidinol |
| abstract | Disclosed is an improved synthesis method of 1-benzyl-3-piperidinol, comprising: coprecipitation of a mixed solution of R-almondol nitrilase crude product and polyethyleneimine; adding oxidized dextran for fixation reaction; washing and drying Obtain cyanotransfer catalyst; carry out cyanotransfer reaction under catalyst action, obtain (R)-1-hydroxyl-4-bromo-1-butyronitrile; react with benzyl halide again, distill under reduced pressure, chromatographic purification, final (R)-1-benzyl-3-piperidinol is obtained. The improved synthetic method not only has higher stereoselectivity, but also has higher yield. |
| priorityDate | 2021-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.