http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113260861-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113260861-B |
| titleOfInvention | Methods for selecting biobinding molecules |
| abstract | The present invention relates to the field of preparation, identification and selection of biological binding molecules, such as in particular antibodies or fragments thereof which selectively bind to somatically hypermutated B cell receptors or B cell receptor complexes. The method is used to select a biological binding molecule that specifically binds to a B cell receptor having a hypermutated region as a target receptor, but does not bind to a B cell receptor that does not have a hypermutated region, and The method is carried out within the context of a cell-based system using immature B cells that are in progenitor/pro-stage and have a "triple knockout" of the RAG2 or RAG1, Lambda5 and SLP65 genes . |
| priorityDate | 2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 470.