http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113249520-A

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filingDate 2021-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ab11d275529710b5f180fd42b3cbae7
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publicationDate 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-113249520-A
titleOfInvention Probe, fluorescent sensor and method for quantitative detection of hepatitis B virus DNA
abstract The invention discloses a probe, a fluorescent sensor and a method for quantitatively detecting hepatitis B virus DNA. The fluorescent sensor includes a first probe enhancement sequence G-rich and a second probe DNA silver nanocluster sequence AgNCs-HBV, G-rich and AgNCs-HBV are dissolved in a buffer, and a target substance to be detected is added, Mix and incubate to construct a fluorescence reaction system, and then perform fluorescence detection to obtain a fluorescence signal. The fluorescence sensor of the invention realizes highly sensitive detection of HBV based on the silver nano-cluster beacon, and tunes the fluorescence of the DNA silver nano-cluster sequence AgNCs-HBV through the ortho-enhanced sequence G-rich, which can improve the detection speed, and the synthesis cost is low. It overcomes the limitations of the traditional PCR method for detection of HBV on site and personnel, and has good versatility, stability and reproducibility, and is suitable for large-scale screening or quantitative detection of hepatitis B and HBV in communities or hospitals.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114002425-A
priorityDate 2021-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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