http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113248440-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-50 |
| filingDate | 2021-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113248440-B |
| titleOfInvention | A kind of synthetic method of 4-formamido antipyrine |
| abstract | The invention discloses a method for synthesizing 4-formamido antipyrine, comprising the following steps: firstly adding methyl formate to raw materials containing 4-amino antipyrine, and carrying out formylation at 30-45° C. Then heating, adding formic acid, and continuing the reaction; finally removing methanol, cooling for crystallization, and centrifuging to obtain 4-formamido antipyrine. In the synthesis method of the present application, methyl formate is used as the acylating reagent of 4-formamido antipyrine, the reaction temperature is lowered during the synthesis of 4-formamido antipyrine, and the 4-amino antipyrine is reduced. The generation of oxidative impurities improves the quality of 4-formamido antipyrine, and by recycling the by-product methyl formate produced in the subsequent process, the consumption of formic acid is greatly reduced, and the cost is saved. |
| priorityDate | 2021-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.