http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113248420-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70fbe08b7c540157200696115221f654 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-36 |
| filingDate | 2021-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3d21b07ae3d056b9b6257047335f9c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_600b7723a329b290210648c864c7a90d |
| publicationDate | 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-113248420-A |
| titleOfInvention | A kind of preparation method of 2-acyl-3-ester base indole derivatives |
| abstract | The invention discloses a preparation method of 2-acyl-3-ester indole derivatives, belonging to the technical field of organic synthesis. The method mainly uses o-amino alkynone compounds as reaction raw materials, and uses Me-DalPhosAuNTf 2 etc. as a catalyst, using toluene, etc. as a solvent, and using 3,5-dichloropyridine nitrogen oxide etc. as an oxidant to react under the condition that the reaction temperature is room temperature, suction filtration to obtain the intermediate-quaternary amine inner salt derivative , and then add a haloacyl compound and use tetrahydrofuran as a solvent to react to obtain 2-acyl-3-ester indole derivatives, which has the characteristics of easy product separation, high yield, wide substrate adaptability, short reaction time and simple reaction process. , has a wide range of application value. |
| priorityDate | 2021-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.